Oligomerization in Health and Disease

Publisher Elsevier Science

Format

eBook

2nd Edition 1st Edition

Quantity

Add New

Publisher

Elsevier Science

Volume

Copyright

2013

ISBN13

9780123869500

Release

Format

eBook

Grade Level

College Freshman - College Senior

DDC
TBD

Overview

This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease.
Front Cover.
Half Title Page.
Title Page.
Copyright.
Contents.
Contributors.
Preface.
1: Structural, Physicochemical, and Evolutionary Aspects of Protein Oligomerization.
2: Evolutionary, Physicochemical, and Functional Mechanisms of Protein Homooligomerization.
3: Structural, Evolutionary, and Assembly Principles of Protein Oligomerization.
4: Physicochemical Principles of Protein Aggregation.
5: Structural Aspects of Amyloid Formation.
6: Oligomerization in Seven-Transmembrane Receptors.
7: Quaternary Structure Predictions and Structural Communication Features of GPCR Dimers.
8: Challenges in the Development of Heteromer-GPCR-Based Drugs.
9: Di/Oligomerization of GPCRs—Mechanisms and Functional Significance.
10: G Protein-Coupled Receptor Heterocomplexes in Neuropsychiatric Disorders.
11: Disease-Specific Heteromerization of G-Protein-Coupled Receptors That Target Drugs of Abuse.
12: Oligomerization in Ion Channels.
13: Social Networking Among Voltage-Activated Potassium Channels.
14: Oligomerization of the Mitochondrial Protein VDAC1: From Structure to Function and Cancer Therapy.
15: Consequences of Dimerization of the Voltage-Gated Proton Channel.
16: Receptor Heteromeric Assembly—How It Works and Why It Matters: The Case of Ionotropic Glutamate Receptors.
17: Oligomerization in Enzymes.
18: The Structural Basis for the Allosteric Regulation of Ribonucleotide Reductase.
19: Oligomerization of Dynamin Superfamily Proteins in Health and Disease.
20: Multimerization of the Dnmt3a DNA Methyltransferase and Its Functional Implications.
21: Oligomerization in Endoplasmic Reticulum Stress Signaling.
22: Oligomerization in Regulatory Proteins.
23: Toll-IL-1-Receptor-Containing Adaptor Molecule-1: A Signaling Adaptor Linking Innate Immunity to Adaptive Immunity.
24: Assembly of Gamma-Tubulin Ring Complexes: Implications for Cell Biology and Disease.
25: Chemokine Oligomerization in Cell Signaling and Migration.
26: Oligomerization of Rab/Effector Complexes
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Oligomerization in Health and Disease

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Table of Contents