Migrant and seasonal farmworkers are largely Latinx men, women, and children. They work in crop, dairy, and livestock production, and are essential to the U.S. agricultural economy-one of the most hazardous and least regulated industries in the United States. Latinx migrant and seasonal farmworkers in the eastern United States experience high rates of illness, injury, and death, indicating widespread occupational injustice. This edition takes a social justice stance and integrates the past ten years of research and intervention to address health, safety, and justice issues for farmworkers. Contributors cover all major areas of health and safety research for migrant and seasonal farmworkers and their families, explore the factors that affect the health and safety of farmworkers and their families, and suggest approaches for further research and educational and policy intervention needed to improve the health and safety of Latinx farmworkers and their families. Among the chapter topics are: occupational injury and illness in Latinx farmworkers in the eastern United States; mental health among Latinx farmworkers in the eastern United States; the health of women farmworkers and women in farmworker families in the eastern United States; the health of children in the Latinx farmworker community in the eastern United States; community-based participatory research with Latinx farmworker communities in the eastern United States; and farm labor and the struggle for justice in the eastern United States. Accessibly written and comprehensive in its scope, this edition will find an engaged audience among researchers, students, and practitioners in public health, occupational health, public policy, and social and behavioral sciences, as well as labor advocates and healthcare providers.