This book recognizes the challenges associated with the concept of spirituality. An awareness of this concept is integral to the provision of person-centered holistic care. However, an APN's ability to provide spiritual care is often impeded by time pressures and the prioritization of clinical tasks. Confusion about the meaning of spirituality and its relationship to religion compound the challenges involved in providing spiritual care leaving APNs feeling ill-equipped to address this area of care. Indeed, many APNs view spirituality as synonymous with religion. This book provides clarity with the assumption that spirituality is innate to all of our patients and is related to what gives them hope, meaning and purpose. Fundamentally it is about being human. An APN's ability to practice with kindness, compassion and empathy will naturally resonate with spiritually competent practice. This book begins with an outline of the definitions of spirituality in addition to the concept of spiritually competent practice. An emphasis on the importance of personal development follows. Case studies from countries across the globe illustrate the benefit of integrating spirituality and provide evidence of the importance and relevance of integrating spirituality into practice. These include discussion and presentations of the related concepts of availability and vulnerability which will give APNs more confidence and competence to integrate spirituality into practice. This book is relevant for APNs, students, educators and researchers.